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Shikha Mittoo MD, MHS, FRCPC

Assistant Professor, Department of Medicine, Division of Rheumatology and Mount Sinai Hospital/University Health Network Interstitial Lung Disease Program

Area of Interest/Background: 

Lung disease occurs in approximately 30-50% of patients with a connective tissue disorder (rheumatoid arthritis, idiopathic inflammatory myositis, lupus, scleroderma, Sjogren's) during the course of the disease and, depending on the type of lung condition, is associated with increased mortality. Emerging data suggests that early events leading to autoimmunity and development of conditions, such as rheumatoid arthritis and myositis, may occur in the respiratory tract. My clinical interests are related to the management of rheumatoid arthritis and rheumatoid arthritis lung disease. This has been a passion of mine since medical school at McMaster University and then during my internal medicine training at Johns Hopkins Hospital.  I have been devoted to patient-centered care and interdisciplinary care and research, graduating with the Daniel Baker Award for Outstanding Patient Care during my residency.

 My research interest is focused on studying the impact of lung disease on clinical outcomes of patients with a rheumatic disease. Specifically, during my fellowship in rheumatology and Masters’ in Clinical Investigation, I studied the role of serum and airway biomarkers in predicting poor clinical outcomes among patients with scleroderma.  I have since expanded my clinical care and research to lupus lung disease and rheumatoid interstitial lung disease and am serving as the co-research director for the Interstitial Lung Disease program at MSH/UHN.