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Clinical Research - Geriatric Study

The Department of Dentistry is conducting a clinical study that may be of interest to patients ranging in age from 65 years old and up who are experiencing instability with their full lower jaw dentures.

For Patients and Caregivers:

If you have lost all of your lower teeth and have had an uncomfortable and poorly lifting lower denture for at least one year, then this study might be for you!

We are proposing to replace your ill-fitting and uncomfortable LOWER denture with one that is supported by two dental implants. The costs associated with this treatment will be 90% LESS than you'd pay otherwise!

All we ask of you in addition to coming in for treatment is to fill out some test forms for memory as well as other forms that can tell us how much improvement you've experienced.

If you're interested in participating in this study, please see the contact information below. You might also wish first to speak with your dentist before calling of course. At the initial contact we will ask some questions to determine your eligibility in this study.

How to Contact Us

Potential participants of their caregivers/family can contact our department at Mount Sinai Hospital (Centre for Advanced Dental Research and Care) so that, if you qualify, an initial screening examination can take place by calling this number: 416-586-3234. We will endeavour to contact you as soon as possible to arrange for a screening.

If you have any further questions, don't hesitate to contact us at [email protected]

For Doctors:

According to the British Society for the study of Prosthetic Dentistry and the McGill University consensus report, the placement of two mandibular implants is the treatment of choice for patients with non-retentive and uncomfortable mandibular dentures. About 50 people are anticipated to participate in this study.

Our overarching goal is to develop a set of neuropsychological and cognitive measures that we believe can be used to predict, a priori, the degree of patient satisfaction with their prostheses. These data can be used to the future to help us discuss treatment needs with family and caregivers as regards need to treat and reasonable expectations of treatment-outcome.

Inclusion Criteria

Patients that meet the following criteria may be eligible for our study: patients should be 65 years or older, edentulous in the mandible for a minimum of 1 year and willing to replace the existing lower full denture. We are looking for patients with no dementia or only at most mild cognitive impairment or mild or moderate dementia.

Exclusion Criteria

Those with severe dementia and/or cognitive impairment, insufficient mandibular bone; any uncontrolled systemic or neurologic disease, conditions that may increase surgical risks (alcoholism), HbA1C levels above 7.0%, diagnosis of neoplasm in the previous 5 years, history of orofacial radiotherapy, symptoms of chronic or acute temporomandibular disorders, body mass index (BMI) less than 20 or more than 32 and smokers will be not included in that the study.


Please direct any potential participants or their caregivers/family to our Department at Mount Sinai Hospital so that an initial screening can take place by calling this number: 416-566-3234. We all endeavour to contact your patient as soon as possible to arrange for a screening.

If you have any other questions, please don't hesitate to contact us at [email protected]