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Premature Ovarian Insufficiency Clinic

Premature Ovarian Insufficiency Clinic

The Premature Ovarian Insufficiency (POI) Clinic is a specialized interdisciplinary clinic, caring for women under the age of 40 who have experienced premature menopause (last menstrual period). The POI Clinic is currently the only clinic of its kind in Canada.

Why Would You or Your Care Team Be Interested in this Clinic?

POI is caused by depletion of eggs in the ovary and the cells around them. This condition may result in symptoms such as hot flashes, night sweats, mood changes, problems sleeping, decreased sexual desire, vaginal dryness, and/or difficulty getting pregnant.

If you haven’t had a period for more than 3-4 months and you are under the age of 40, you should contact your primary care physician. He/she may conduct bloodwork, including pregnancy tests and special hormone tests. If the results indicate concern about your ovarian function, you could be a candidate for this clinic.

The POI Clinic has five primary aims:

  1. Find the possible cause and verify the diagnosis
  2. Provide symptomatic relief
  3. Formulate long-term treatments to prevent future health problems
  4. Counsel and refer about fertility
  5. Research

Interdisciplinary Care

The POI Clinic includes expert physicians in endocrinology and gynaecology, and further specialist referral if necessary.

Teaching Clinic

This clinic is University of Toronto affiliated. All types of medical learners (students, residents, fellows) may be present.

Referral-Based Clinic

In order to attend this clinic, you require a referral from your primary care physician or specialist.

Before Coming to Clinic

The POI Clinic provides interdisciplinary care through on-site specialists and counselling about the disorder, as well as personalized referrals.

What to Expect 

Learn more about your first appointment.

Referral Criteria 

Patient referral criteria for referring providers.

Meet the Team 

Meet our interdisciplinary team of endocrinologists and gynaecologists.

More About POI 

Learn more about POI, including its causes, symptoms and treatments.


View Frequently Asked Questions about POI and/or the clinic.

In the news

Refer a Patient to the POI Clinic

Download this form to refer a patient to our clinic.

Find Us

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 Mount Sinai Hospital
 700 University Avenue,
 8th Floor: Women's Unit
 Toronto, Ontario, Canada M5G 1Z5

telephone icon  416-586-4800 Ext: 4621


Tuesday: 1 p.m. - 5 p.m.

The POI Clinic runs on one to two Tuesdays per month. The Clinic is located in the old Hydro building. This is the outpatient facility for Mount Sinai Hospital, Department of Gynaecology. Referral is required. Participation in research to further understand and treat POI is an active goal of this clinic.